PCl3-mediated transesterification and aminolysis of tert-butyl esters via acid chloride formation
نویسندگان
چکیده
منابع مشابه
Deprotection of Benzyl and t-Butyl Phosphate, Phosphite, and Sulfite Esters by Silica Chloride
Deprotection of phosphate, phosphate, and sulfite esters by silica chloride is described. Silica chloride is a mild, selective, and effective reagent for cleavage of benzyl and t-butyl esters of the above compounds.
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The pKAH-values of some substituted phenylacetic acid derivatives have been determined in the system water /dimethyl sulphoxide / 0. 11 M tetramethylammonium hydroxide. The acidity depends strongly on the polarity of the substituent in the phenyl group, Hammett p-valucs from 4.8 to 5 .8, and in the case of the same s<1bstituent decreasf's in the order nit! ik, terr-butyl ester, dimethylami<'e e...
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A novel organogelator based on tert-butyl esters of asparagines has been synthesized and its organogelation abilities have been investigated. The rheological characterization has confirmed the gelation behavior, and its thixotropic properties. Furthermore, the morphological studies performed reveal a spherical structure. Thus, this organogelator can be considered as a new example of the emergin...
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Solid-phase peptide synthesis in the N-to-C direction, opposite to the classical C-to-N direction of peptide synthesis, provides the synthetically versatile C-terminal carboxyl group for further modification into C-terminally modified peptide mimetics. These are of general interest as potential bioactive agents, particularly as protease inhibitors. Elaboration of peptide mimetics on the solid-p...
متن کاملCLEAVAGE OF ESTERS AND ETHERS WITH SILICA CHLORIDE
Silica chloride converted benzyl or tert-butyl esters to the corresponding acid chlorides and alkyl chlorides. It also converted benzyl or tert-butyl phenyl ethers to the corresponding allcyl chlorides and phenol
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ژورنال
عنوان ژورنال: Journal of Chemical Research
سال: 2021
ISSN: 1747-5198,2047-6507
DOI: 10.1177/1747519820987530